Cancer Resources

Providing Solutions for Diseases with Unmet Medical Need

Next generation human enzymes have the potential to advance treatment options for cancer. We believe these engineered human enzymes can lead to targeted cancer therapies with the power to improve clinical outcomes and patients’ lives.

But it can’t happen without individuals, families, physicians, and scientists coming together as a community to help those with a diagnosis of cancer.

To this end we’ve compiled information about our product candidates’ clinical trials and related resources.

Current Clinical Trials

To develop an investigational therapy into a fully approved therapeutic option a rigorous “phased” approach is required. In each phase, specific goals must be accomplished before the next phase can begin.

Included in our portfolio of engineered human enzymes with high therapeutic potential are treatment candidates in different phases of development for a variety of cancer indications. Details below:

  • A Phase 1/2 Study of Pegzilarginase (AEB1102, Co-ArgI-PEG) in Combination With Pembrolizumab in the Treatment of Patients With Extensive Disease (ED) Small Cell Lung Cancer (SCLC) – NCT03371979 –  Active, Not Recruiting

Thank you to the patients, families and physicians who contribute to our collective knowledge and to the potential of future therapies by considering involvement in clinical trials.

Patient Resources

Let us know if there is another organization or resource that you would like to see listed here or to speak with someone in Patient Engagement